Enzymatic Characterization of Recombinant Food Vacuole Plasmepsin 4 from the Rodent Malaria Parasite Plasmodium berghei

Enzymatic Characterization of Recombinant Food Vacuole Plasmepsin 4 from the Rodent Malaria Parasite Plasmodium berghei

The rodent malaria parasite Plasmodium berghei is a practical model organism for experimental studies of human malaria. Plasmepsins are a class of aspartic proteinase isoforms that exert multiple pathological effects in malaria parasites. Plasmepsins residing in the food vacuole (FV) of the parasite...

Full description

Bibliographic Details
Main Authors:	Liu, Peng, Robbins, Arthur H., Marzahn, Melissa R., McClung, Scott H., Yowell, Charles A., Stevens, Stanley M., Dame, John B., Dunn, Ben M.
Format:	Online
Language:	English
Published:	Public Library of Science 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624963/

Similar Items

Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum
by: Klemba, Michael, et al.
Published: (2004)

Plasmodium falciparum ookinete expression of plasmepsin VII and plasmepsin X
by: Li, Fengwu, et al.
Published: (2016)

Disruption of plasmepsin-4 and merozoites surface protein-7 genes in Plasmodium berghei induces combined virulence-attenuated phenotype
by: Spaccapelo, Roberta, et al.
Published: (2011)

Visualization of Malaria Parasites in the Skin Using the Luciferase Transgenic Parasite, Plasmodium berghei
by: Matsuoka, Hiroyuki, et al.
Published: (2015)

Wild Anopheles funestus Mosquito Genotypes Are Permissive for Infection with the Rodent Malaria Parasite, Plasmodium berghei
by: Xu, Jiannong, et al.
Published: (2013)

The Exported Protein PbCP1 Localises to Cleft-Like Structures in the Rodent Malaria Parasite Plasmodium berghei
by: Haase, Silvia, et al.
Published: (2013)

A Stem Cell Strategy Identifies Glycophorin C as a Major Erythrocyte Receptor for the Rodent Malaria Parasite Plasmodium berghei
by: Yiangou, Loukia, et al.
Published: (2016)

Improved negative selection protocol for Plasmodium berghei in the rodent malarial model
by: Orr, Rachael Y, et al.
Published: (2012)

Plasmodium berghei Δp52&p36 Parasites Develop Independent of a Parasitophorous Vacuole Membrane in Huh-7 Liver Cells
by: Ploemen, Ivo H. J., et al.
Published: (2012)

The prosegment catalyzes native folding of Plasmodium falciparum plasmepsin II
by: Jaafar, Ahmad Haniff, et al.
Published: (2016)

Experimental Determination of the Membrane Topology of the Plasmodium Protease Plasmepsin V
by: Tarr, Sarah J., et al.
Published: (2015)

Evaluation of immunity against malaria using luciferase-expressing Plasmodium berghei parasites
by: Ploemen, Ivo, et al.
Published: (2011)

Phagotrophy and Two New Structures in the Malaria Parasite Plasmodium berghei
by: Rudzinska, Maria A., et al.
Published: (1959)

Mosquito transmission of the rodent malaria parasite Plasmodium chabaudi
by: Spence, Philip J, et al.
Published: (2012)

Plasmepsin V, a Secret Weapon Against Malaria
by: Sedwick, Caitlin
Published: (2014)

Extracellular ATP triggers proteolysis and cytosolic Ca2+ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites
by: Cruz, Laura Nogueira, et al.
Published: (2012)

Plasmodium berghei bio-burden correlates with parasite lactate dehydrogenase: application to murine Plasmodium diagnostics
by: De, Sai Lata, et al.
Published: (2016)

Addition of histamine to subcutaneously injected Plasmodium berghei sporozoites increases the parasite liver load and could facilitate whole-parasite vaccination
by: Pfeil, Johannes, et al.
Published: (2015)

The utility of Plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment
by: Goodman, Anna L., et al.
Published: (2013)

Disulfide Linkages in Plasmodium falciparum Plasmepsin-I Are Essential Elements for Its Processing Activity and Multi-Milligram Recombinant Production Yield
by: Lolupiman, Sirisak, et al.
Published: (2014)

Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors
by: Bedi, Rajiv K., et al.
Published: (2016)

Penglibatan protein fosfotirosin dalam infeksi plasmodium berghei
by: Hasidah Mohd Sidek,, et al.
Published: (2000)

Intravital Observation of Plasmodium berghei Sporozoite Infection of the Liver
by: Frevert, Ute, et al.
Published: (2005)

The role of metacaspase 1 in Plasmodium berghei development and apoptosis
by: Le Chat, Ludovic, et al.
Published: (2007)

Deciphering the targets of retroviral protease inhibitors in Plasmodium berghei.
by: Noah Machuki Onchieku, et al.

Antimalarial Potential of Carica papaya and Vernonia amygdalina in Mice Infected with Plasmodium berghei
by: Okpe, Oche, et al.
Published: (2016)

Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites
by: Fonager, Jannik, et al.
Published: (2011)

Drug-induced permeabilization of parasite's digestive vacuole is a key trigger of programmed cell death in Plasmodium falciparum
by: Ch'Ng, J-H, et al.
Published: (2011)

Direct Tests of Enzymatic Heme Degradation by the Malaria Parasite Plasmodium falciparum*
by: Sigala, Paul A., et al.
Published: (2012)

Anopheles gambiae Immune Responses to Human and Rodent Plasmodium Parasite Species
by: Dong, Yuemei, et al.
Published: (2006)

Effects of Artesunate on Parasite Recrudescence and Dormancy in the Rodent Malaria Model Plasmodium vinckei
by: LaCrue, Alexis N., et al.
Published: (2011)

The Unique Structure of the Apicoplast Genome of the Rodent Malaria Parasite Plasmodium chabaudi chabaudi
by: Sato, Shigeharu, et al.
Published: (2013)

The Plasmodium PHIST and RESA-Like Protein Families of Human and Rodent Malaria Parasites
by: Moreira, Cristina K., et al.
Published: (2016)

Plasmodium berghei: Parasite clearance after treatment with dihydroartemisinin in an asplenic murine malaria model
by: Moore, Brioni, et al.
Published: (2008)

Characterisation of the unique large Armadillo repeat protein (LARP) in the malaria parasite Plasmodium berghei
by: Stock, Jessica
Published: (2016)

Roles of the Amino Terminal Region and Repeat Region of the Plasmodium berghei Circumsporozoite Protein in Parasite Infectivity
by: Aldrich, Cassandra, et al.
Published: (2012)

Protection from Experimental Cerebral Malaria with a Single Dose of Radiation-Attenuated, Blood-Stage Plasmodium berghei Parasites
by: Gerald, Noel J., et al.
Published: (2011)

Flow cytometry-assisted rapid isolation of recombinant Plasmodium berghei parasites exemplified by functional analysis of aquaglyceroporin
by: Kenthirapalan, Sanketha, et al.
Published: (2012)

Correction: Aberrant Sporogonic Development of Dmc1 (a Meiotic Recombinase) Deficient Plasmodium berghei Parasites
by: Mlambo, Godfree, et al.
Published: (2013)

Aberrant Sporogonic Development of Dmc1 (a Meiotic Recombinase) Deficient Plasmodium berghei Parasites
by: Mlambo, Godfree, et al.
Published: (2012)