Roles of the Amino Terminal Region and Repeat Region of the Plasmodium berghei Circumsporozoite Protein in Parasite Infectivity

The circumsporozoite protein (CSP) plays a key role in malaria sporozoite infection of both mosquito salivary glands and the vertebrate host. The conserved Regions I and II have been well studied but little is known about the immunogenic central repeat region and the N-terminal region of the protein...

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Bibliographic Details
Main Authors: Aldrich, Cassandra, Magini, Alessandro, Emiliani, Carla, Dottorini, Tania, Bistoni, Francesco, Crisanti, Andrea, Spaccapelo, Roberta
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290588/