HER-2/neu Amplification Testing in Breast Cancer by Multiplex Ligation-Dependent Probe Amplification in Comparison with Immunohistochemistry and In Situ Hybridization

HER-2/neu Amplification Testing in Breast Cancer by Multiplex Ligation-Dependent Probe Amplification in Comparison with Immunohistochemistry and In Situ Hybridization

Background: Assessment of HER-2/neu status in invasive breast cancer is crucial to establish eligibility for trastuzumab and taxane based chemotherapy. Next to immunohistochemistry (IHC) to evaluate protein overexpression, a second line gene amplification test is required for cases with equivocal p...

Full description

Bibliographic Details
Main Authors: Moelans, Cathy B., de Weger, Roel A., van Blokland, Marja T.M., Ezendam, Chantal, Elshof, Sabrina, Tilanus, Marcel G. J., van Diest, Paul J.
Format: Online
Language:English
Published: IOS Press 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618800/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618800/

Similar Items