ESR1 Amplification is Rare in Breast Cancer and is Associated with High Grade and High Proliferation: A Multiplex Ligation-Dependent Probe Amplification Study

ESR1 Amplification is Rare in Breast Cancer and is Associated with High Grade and High Proliferation: A Multiplex Ligation-Dependent Probe Amplification Study

Background: Expression of estrogen receptor alpha (ERα) is predictive for endocrine therapy response and an important prognostic factor in breast cancer. Overexpression of ERα can be caused by estrogen receptor 1 (ESR1) gene amplification and was originally reported to be a frequent event associate...

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Bibliographic Details
Main Authors: Moelans, Cathy B., Monsuur, Hanneke N., de Pinth, Johannes H., Radersma, Remco D., de Weger, Roel A., van Diest, Paul J.
Format: Online
Language:English
Published: IOS Press 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605667/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605667/

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