Chromosomal Instability, Aneuploidy, and Gene Mutations in Human Sporadic Colorectal Adenomas
Whether in vivo specific gene mutations lead to chromosomal instability (CIN) and aneuploidy or viceversa is so far not proven. We hypothesized that aneuploidy among human sporadic colorectal adenomas and KRAS2 and APC mutations were not independent. Additionally, we investigated if 1p34–36 deletion...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
IOS Press
2004
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617587/ |