KRAS, p53 and BRAF Gene Mutations and Aneuploidy in Sporadic Colorectal Cancer Progression

Background: The origin and mechanisms of chromosomal instability are still widely unknown. We previously investigated a limited number of human sporadic colorectal cancers (CRCs) and observed a statistically different occurrence of KRAS and p53 mutations among predetermined subgroups of tumors with...

Full description

Bibliographic Details
Main Authors: Calistri, Daniele, Rengucci, Claudia, Seymour, Ian, Leonardi, Elena, Truini, Mauro, Malacarne, Davide, Castagnola, Patrizio, Giaretti, Walter
Format: Online
Language:English
Published: IOS Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615153/