Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations

Although Bacillus Calmette-Guérin (BCG) vaccines against tuberculosis have been available for more than 90 years, their effectiveness has been hindered by variable protective efficacy and a lack of lasting memory responses. One factor contributing to this variability may be the diversity of the BCG...

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Bibliographic Details
Main Authors: Abdallah, Abdallah M., Hill-Cawthorne, Grant A., Otto, Thomas D., Coll, Francesc, Guerra-Assunção, José Afonso, Gao, Ge, Naeem, Raeece, Ansari, Hifzur, Malas, Tareq B., Adroub, Sabir A., Verboom, Theo, Ummels, Roy, Zhang, Huoming, Panigrahi, Aswini Kumar, McNerney, Ruth, Brosch, Roland, Clark, Taane G., Behr, Marcel A., Bitter, Wilbert, Pain, Arnab
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614345/