The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics
The Kelch-like ECH associated protein 1 (Keap1)–NF-E2 p45-related factor 2 (Nrf2) pathway regulates networks of proteins that protect against the cumulative damage of oxidants, electrophiles and misfolded proteins. The interaction between transcription factor Nrf2 and its main negative cytoplasmic r...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613514/ |