Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus

Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus

Type 1 diabetes is caused by autoreactive T cells that destroy pancreatic beta cells. Animal models suggested that a CD4+CD25+ population has a regulatory function capable of preventing activation and effector functions of autoreactive T cells. However, the role of CD4+CD25high T cells in autoimmuni...

Full description

Bibliographic Details
Main Authors: Perri, Valentina, Russo, Benedetta, Crinò, Antonino, Schiaffini, Riccardo, Giorda, Ezio, Cappa, Marco, Rosado, Maria Manuela, Fierabracci, Alessandra
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613325/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613325/

Similar Items