Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice

Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice

Recently, the importance of lysosomes in the context of the metabolic syndrome has received increased attention. Increased lysosomal cholesterol storage and cholesterol crystallization inside macrophages have been linked to several metabolic diseases, such as atherosclerosis and non-alcoholic fatty...

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Bibliographic Details
Main Authors: Walenbergh, Sofie M. A., Houben, Tom, Hendrikx, Tim, Jeurissen, Mike L. J., van Gorp, Patrick J., Vaes, Nathalie, Olde Damink, Steven W. M., Verheyen, Fons, Koek, Ger H., Lütjohann, Dieter, Grebe, Alena, Latz, Eicke, Shiri-Sverdlov, Ronit
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613241/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613241/

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