Predictive Biomarkers to Chemoradiation in Locally Advanced Rectal Cancer

Predictive Biomarkers to Chemoradiation in Locally Advanced Rectal Cancer

There has been a high local recurrence rate in rectal cancer. Besides improvements in surgical techniques, both neoadjuvant short-course radiotherapy and long-course chemoradiation improve oncological results. Approximately 40–60% of rectal cancer patients treated with neoadjuvant chemoradiation ach...

Full description

Bibliographic Details
Main Authors:	Conde-Muíño, Raquel, Cuadros, Marta, Zambudio, Natalia, Segura-Jiménez, Inmaculada, Cano, Carlos, Palma, Pablo
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609421/

Similar Items

Microarray Profiling of Mononuclear Peripheral Blood Cells Identifies Novel Candidate Genes Related to Chemoradiation Response in Rectal Cancer
by: Palma, Pablo, et al.
Published: (2013)

Expression Profiling of Rectal Tumors Defines Response to Neoadjuvant Treatment Related Genes
by: Palma, Pablo, et al.
Published: (2014)

Preoperative Chemoradiation in Locally Advanced Rectal Cancer: Efficacy and Safety
by: Peponi, Evangelia, et al.
Published: (2015)

Nomogram to predict ypN status after chemoradiation in patients with locally advanced rectal cancer
by: Jwa, E, et al.
Published: (2014)

Implications for selecting local excision in locally advanced rectal cancer after preoperative chemoradiation
by: Wan, Juefeng, et al.
Published: (2015)

The use of personalized biomarkers and liquid biopsies to monitor treatment response and disease recurrence in locally advanced rectal cancer after neoadjuvant chemoradiation
by: Carpinetti, Paola, et al.
Published: (2015)

Preventing parastomal hernias with systematic intraperitoneal specifically designed mesh
by: Raquel Conde-Muíño, et al.
Published: (2017-04-01)

Neoadjuvant chemoradiation with Gemcitabine for locally advanced pancreatic cancer
by: Habermehl, Daniel, et al.
Published: (2012)

Diffusion-Weighted MRI for Selection of Complete Responders After Chemoradiation for Locally Advanced Rectal Cancer: A Multicenter Study
by: Lambregts, Doenja M. J., et al.
Published: (2011)

Preoperative Chemoradiation in Locally Advanced Rectal Cancer: A Comparison of Bolus 5-Fluorouracil/Leucovorin and Capecitabine
by: Yoney, Adnan, et al.
Published: (2014)

Optimal timing of surgery after neoadjuvant chemoradiation therapy in locally advanced rectal cancer
by: Jeong, Duck Hyoun, et al.
Published: (2013)

A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis
by: Sun Young Kim, et al.
Published: (2017-03-01)

Outcome of neoadjuvant chemoradiation in MRI staged locally advanced rectal cancer: Retrospective analysis of 123 Chinese patients
by: Shing Fung Lee, et al.
Published: (2018-09-01)

Discriminating cancer-related and cancer-unrelated chemoradiation-response genes for locally advanced rectal cancers
by: Guo, You, et al.
Published: (2016)

Severe myositis of the hip flexors after pre-operative chemoradiation therapy for locally advanced rectal cancer: case report
by: Florczynski, Matthew M., et al.
Published: (2016)

Restaging locally advanced rectal cancer by different imaging modalities after preoperative chemoradiation: a comparative study
by: Dickman, Ram, et al.
Published: (2013)

Preoperative chemoradiation for locally advanced rectal cancer: comparison of three radiation dose and fractionation schedules
by: Park, Shin-Hyung, et al.
Published: (2016)

Endoscopic Criteria for Evaluating Tumor Stage after Preoperative Chemoradiation Therapy in Locally Advanced Rectal Cancer
by: Han, Kyung Su, et al.
Published: (2016)

Change of telomerase activity in rectal cancer with chemoradiation therapy.
by: Kim, H. R., et al.
Published: (2000)

New Perspectives on Predictive Biomarkers of Tumor Response and Their Clinical Application in Preoperative Chemoradiation Therapy for Rectal Cancer
by: Kim, Nam Kyu, et al.
Published: (2015)

Effectiveness of the Apparent Diffusion Coefficient for Predicting the Response to Chemoradiation Therapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-analysis
by: Xie, Haiting, et al.
Published: (2015)

A randomized phase II study of capecitabine-based chemoradiation with or without bevacizumab in resectable locally advanced rectal cancer: clinical and biological features
by: Salazar, Ramon, et al.
Published: (2015)

Bilateral Blindness Following Chemoradiation for Locally Advanced Oropharyngeal Carcinoma
by: Zeng, K. Liang, et al.
Published: (2015)

Evaluation of potential circulating biomarkers for prediction of response to chemoradiation in patients with glioblastoma
by: van Linde, Myra E., et al.
Published: (2016)

Predictors of Complete Response and Disease Recurrence Following Chemoradiation for Rectal Cancer
by: Bitterman, Danielle S., et al.
Published: (2015)

Neoadjuvant chemoradiation therapy and pathological complete response in rectal cancer
by: Ferrari, Linda, et al.
Published: (2015)

Aspirin as a neoadjuvant agent during preoperative chemoradiation for rectal cancer
by: Restivo, Angelo, et al.
Published: (2015)

Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial
by: Verstraete, M, et al.
Published: (2015)

Neoadjuvant chemoradiation for rectal cancer in patients aged 75 years or older
by: Lombardi, Raffaele, et al.
Published: (2009)

Clinical Impact of Tumor Regression Grade after Preoperative Chemoradiation for Locally Advanced Rectal Cancer: Subset Analyses in Lymph Node Negative Patients
by: Min, Byung Soh, et al.
Published: (2011)

Circulating Cell-Free DNA in Plasma of Locally Advanced Rectal Cancer Patients Undergoing Preoperative Chemoradiation: A Potential Diagnostic Tool for Therapy Monitoring
by: Zitt, Matthias, et al.
Published: (2008)

Role of adjuvant chemotherapy in locally advanced rectal cancer with ypT0-3N0 after preoperative chemoradiation therapy and surgery
by: Chang Gon Kim, et al.
Published: (2017-09-01)

Oncologic Impact of Fewer Than 12 Lymph Nodes in Patients Who Underwent Neoadjuvant Chemoradiation Followed by Total Mesorectal Excision for Locally Advanced Rectal Cancer
by: Kim, Woo Ram, et al.
Published: (2015)

Baseline neutrophil-lymphocyte ratio (≥2.8) as a prognostic factor for patients with locally advanced rectal cancer undergoing neoadjuvant chemoradiation
by: Shen, Lijun, et al.
Published: (2014)

MicroRNA-31 Emerges as a Predictive Biomarker of Pathological Response and Outcome in Locally Advanced Rectal Cancer
by: Caramés, Cristina, et al.
Published: (2016)

Predictive value of vrk 1 and 2 for rectal adenocarcinoma response to neoadjuvant chemoradiation therapy: a retrospective observational cohort study
by: del Puerto-Nevado, Laura, et al.
Published: (2016)

XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy
by: Qin, Chang-Jiang, et al.
Published: (2015)

An Update on Preoperative Radiotherapy for Locally Advanced Rectal Cancer
by: Yeo, Seung-Gu, et al.
Published: (2012)

Locally advanced rectal cancer: management challenges
by: Kokelaar, RF, et al.
Published: (2016)

Long-Term Outcome of Patients with Complete Pathologic Response after Neoadjuvant Chemoradiation for cT3 Rectal Cancer: Implications for Local Excision Surgical Strategies
by: Belluco, Claudio, et al.
Published: (2011)