Discovery and optimisation studies of antimalarial phenotypic hits
There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were identified. Characterization of these compounds is discussed, along with approaches to optimise the ph...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Editions Scientifiques Elsevier
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607724/ |