Structure–Activity Relationship Studies of Pyrrolone Antimalarial Agents

Structure–Activity Relationship Studies of Pyrrolone Antimalarial Agents

Previously reported pyrrolones, such as TDR32570, exhibited potential as antimalarial agents; however, while these compounds have potent antimalarial activity, they suffer from poor aqueous solubility and metabolic instability. Here, further structure–activity relationship studies are described that...

Full description

Bibliographic Details
Main Authors: Murugesan, Dinakaran, Kaiser, Marcel, White, Karen L, Norval, Suzanne, Riley, Jennifer, Wyatt, Paul G, Charman, Susan A, Read, Kevin D, Yeates, Clive, Gilbert, Ian H
Format: Online
Language:English
Published: WILEY-VCH Verlag 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963473/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963473/

Similar Items