Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

Bile acids are well-recognized stimuli of glucagon-like peptide-1 (GLP-1) secretion. This action has been attributed to activation of the G protein–coupled bile acid receptor GPBAR1 (TGR5), although other potential bile acid sensors include the nuclear farnesoid receptor and the apical sodium-couple...

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Bibliographic Details
Main Authors: Brighton, Cheryl A., Rievaj, Juraj, Kuhre, Rune E., Glass, Leslie L., Schoonjans, Kristina, Holst, Jens J., Gribble, Fiona M., Reimann, Frank
Format: Online
Language:English
Published: Endocrine Society 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606749/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606749/

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