Bile acid-FXRα pathways regulate male sexual maturation in mice

The bile acid receptor Farnesol-X-Receptor alpha (FRXα) is a member of the nuclear receptor superfamily. FRXα is expressed in the interstitial compartment of the adult testes, which contain the Leydig cells. In adult, short term treatment (12 hours) with FRXα agonist inhibits the expression of stero...

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Bibliographic Details
Main Authors: Baptissart, Marine, Martinot, Emmanuelle, Vega, Aurélie, Sédes, Lauriane, Rouaisnel, Betty, de Haze, Angélique, Baron, Silvère, Schoonjans, Kristina, Caira, Françoise, Volle, David H.
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991395/