Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1

Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1

Limiting dilution assays are widely used in infectious disease research. These assays are crucial for current HIV-1 cure research in particular. Here we offer new tools to help investigators design and analyze dilution assays based on their specific research needs.

Bibliographic Details
Main Authors: Rosenbloom, Daniel I. S., Elliott, Oliver, Hill, Alison L., Henrich, Timothy J., Siliciano, Janet M., Siliciano, Robert F.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602119/
id pubmed-4602119
recordtype oai_dc
spelling pubmed-46021192015-10-16 Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1 Rosenbloom, Daniel I. S. Elliott, Oliver Hill, Alison L. Henrich, Timothy J. Siliciano, Janet M. Siliciano, Robert F. Review Articles Limiting dilution assays are widely used in infectious disease research. These assays are crucial for current HIV-1 cure research in particular. Here we offer new tools to help investigators design and analyze dilution assays based on their specific research needs. Oxford University Press 2015-08-26 /pmc/articles/PMC4602119/ /pubmed/26478893 http://dx.doi.org/10.1093/ofid/ofv123 Text en © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Rosenbloom, Daniel I. S.
Elliott, Oliver
Hill, Alison L.
Henrich, Timothy J.
Siliciano, Janet M.
Siliciano, Robert F.
spellingShingle Rosenbloom, Daniel I. S.
Elliott, Oliver
Hill, Alison L.
Henrich, Timothy J.
Siliciano, Janet M.
Siliciano, Robert F.
Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1
author_facet Rosenbloom, Daniel I. S.
Elliott, Oliver
Hill, Alison L.
Henrich, Timothy J.
Siliciano, Janet M.
Siliciano, Robert F.
author_sort Rosenbloom, Daniel I. S.
title Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1
title_short Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1
title_full Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1
title_fullStr Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1
title_full_unstemmed Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1
title_sort designing and interpreting limiting dilution assays: general principles and applications to the latent reservoir for human immunodeficiency virus-1
description Limiting dilution assays are widely used in infectious disease research. These assays are crucial for current HIV-1 cure research in particular. Here we offer new tools to help investigators design and analyze dilution assays based on their specific research needs.
publisher Oxford University Press
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602119/
_version_ 1613486740568276992

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