Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1

Limiting dilution assays are widely used in infectious disease research. These assays are crucial for current HIV-1 cure research in particular. Here we offer new tools to help investigators design and analyze dilution assays based on their specific research needs.

Bibliographic Details
Main Authors: Rosenbloom, Daniel I. S., Elliott, Oliver, Hill, Alison L., Henrich, Timothy J., Siliciano, Janet M., Siliciano, Robert F.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602119/