APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments
APPL1 vesicles represent a distinct population of Rab5-positive early endosomes that undergoes fusion and fission and sorts and exchanges cargo with EEA1 endosomes, suggesting a new organization of the endocytic pathway.
Bibliographic Details
| Main Authors: |
Kalaidzidis, Inna,
Miaczynska, Marta,
Brewińska-Olchowik, Marta,
Hupalowska, Anna,
Ferguson, Charles,
Parton, Robert G.,
Kalaidzidis, Yannis,
Zerial, Marino |
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| Format: | Online
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| Language: | English |
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| Published: |
The Rockefeller University Press
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602042/
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