APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments
APPL1 vesicles represent a distinct population of Rab5-positive early endosomes that undergoes fusion and fission and sorts and exchanges cargo with EEA1 endosomes, suggesting a new organization of the endocytic pathway.
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602042/ |