Attenuation of p38α MAPK stress response signaling delays the in vivo aging of skeletal muscle myofibers and progenitor cells

Attenuation of p38α MAPK stress response signaling delays the in vivo aging of skeletal muscle myofibers and progenitor cells

Functional competence and self-renewal of mammalian skeletal muscle myofibers and progenitor cells declines with age. Progression of the muscle aging phenotype involves the decline of juvenile protective factors i.e., proteins whose beneficial functions translate directly to the quality of life, and...

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Bibliographic Details
Main Authors: Papaconstantinou, John, Wang, Chen Z., Zhang, Min, Yang, San, Deford, James, Bulavin, Dmitry V., Ansari, Naseem H.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600628/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600628/

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