Therapeutic targeting of replicative immortality

Therapeutic targeting of replicative immortality

One of the hallmarks of malignant cell populations is the ability to undergo continuous proliferation. This property allows clonal lineages to acquire sequential aberrations that can fuel increasingly autonomous growth, invasiveness, and therapeutic resistance. Innate cellular mechanisms have evolve...

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Bibliographic Details
Main Authors: Yaswen, Paul, MacKenzie, Karen L., Keith, W. Nicol, Hentosh, Patricia, Rodier, Francis, Zhu, Jiyue, Firestone, Gary L., Matheu, Ander, Carnero, Amancio, Bilsland, Alan, Sundin, Tabetha, Honoki, Kanya, Fujii, Hiromasa, Georgakilas, Alexandros G., Amedei, Amedeo, Amin, Amr, Helferich, Bill, Boosani, Chandra S., Guha, Gunjan, Ciriolo, Maria Rosa, Chen, Sophie, Mohammed, Sulma I., Azmi, Asfar S., Bhakta, Dipita, Halicka, Dorota, Niccolai, Elena, Aquilano, Katia, Ashraf, S. Salman, Nowsheen, Somaira, Yang, Xujuan
Format: Online
Language:English
Published: Academic Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600408/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600408/

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