Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population‐based cohort
Alcohol dependence is frequently co‐morbid with cognitive impairment. The relationship between these traits is complex as cognitive dysfunction may arise as a consequence of heavy drinking or exist prior to the onset of dependence. In the present study, we tested the genetic overlap between cognitiv...
Main Authors: | Clarke, Toni‐Kim, Smith, Andrew H., Gelernter, Joel, Kranzler, Henry R., Farrer, Lindsay A., Hall, Lynsey S., Fernandez‐Pujals, Ana M., MacIntyre, Donald J., Smith, Blair H., Hocking, Lynne J., Padmanabhan, Sandosh, Hayward, Caroline, Thomson, Pippa A., Porteous, David J., Deary, Ian J., McIntosh, Andrew M. |
---|---|
Format: | Online |
Language: | English |
Published: |
John Wiley and Sons Inc.
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600406/ |
Similar Items
-
Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index
by: Clarke, T-K, et al.
Published: (2015) -
Polygenic risk for coronary artery disease is associated with cognitive ability in older adults
by: Hagenaars, Saskia P, et al.
Published: (2016) -
Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population
by: Clarke, T-K, et al.
Published: (2016) -
Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression
by: Zeng, Yanni, et al.
Published: (2016) -
Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures
by: Kapoor, M, et al.
Published: (2016)