Impact of cross-disorder polygenic risk on frontal brain activation with specific effect of schizophrenia risk

Evidence suggests that there is shared genetic aetiology across the major psychiatric disorders conferred by additive effects of many common variants. Measuring their joint effects on brain function may identify common neural risk mechanisms. We investigated the effects of a cross-disorder polygenic...

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Bibliographic Details
Main Authors: Whalley, Heather C., Hall, Lynsey, Romaniuk, Liana, Macdonald, Alix, Lawrie, Stephen M., Sussmann, Jessika E., McIntosh, Andrew M.
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396692/