Persistence of diet-induced obesity despite access to voluntary activity in mice lacking sarcolipin

Several rodent models of obesity have been shown to develop excessive adiposity only when voluntary cage ambulation is restricted. We have previously shown that mice lacking the sarco(endo)plasmic reticulum Ca2+-ATPase pump regulatory protein sarcolipin (Sln–/–), an uncoupler of Ca2+ uptake, develop...

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Bibliographic Details
Main Authors: Gamu, Daniel, Trinh, Anton, Bombardier, Eric, Tupling, A Russell
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600390/