Dictyostelium Nramp1, which is structurally and functionally similar to mammalian DMT1 transporter, mediates phagosomal iron efflux
The Nramp (Slc11) protein family is widespread in bacteria and eukaryotes, and mediates transport of divalent metals across cellular membranes. The social amoeba Dictyostelium discoideum has two Nramp proteins. Nramp1, like its mammalian ortholog (SLC11A1), is recruited to phagosomal and macropinoso...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Company of Biologists
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582194/ |