Host Resistance to Intracellular Infection: Mutation of Natural Resistance-associated Macrophage Protein 1 (Nramp1) Impairs Phagosomal Acidification
The mechanisms underlying the survival of intracellular parasites such as mycobacteria in host macrophages remain poorly understood. In mice, mutations at the Nramp1 gene (for natural resistance-associated macrophage protein), cause susceptibility to mycobacterial infections. Nramp1 encodes an integ...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
1998
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212455/ |