Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidase

Twin Cx9C proteins constitute a large protein family in the intermembrane space of mitochondria. One of these proteins, Cox19, serves as interaction partner of the copper transfer protein Cox11. The results suggest that a redox-regulated interplay of Cox19 and Cox11 is critical for copper insertion...

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Bibliographic Details
Main Authors: Bode, Manuela, Woellhaf, Michael W., Bohnert, Maria, van der Laan, Martin, Sommer, Frederik, Jung, Martin, Zimmermann, Richard, Schroda, Michael, Herrmann, Johannes M.
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571295/