A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase

A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase

The biogenesis of Cox4 is unknown. Cox4, mtHsp70, and Mge1 form a complex that promotes the assembly of cytochrome c oxidase. In the absence of the mature cytochrome c oxidase, Cox4 arrests at the chaperone complex. This complex delivers Cox4 into the assembly line of complex IV when needed.

Bibliographic Details
Main Authors: Böttinger, Lena, Guiard, Bernard, Oeljeklaus, Silke, Kulawiak, Bogusz, Zufall, Nicole, Wiedemann, Nils, Warscheid, Bettina, van der Laan, Martin, Becker, Thomas
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756914/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756914/

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