The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis

The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis

Viral fulminant hepatitis (FH) is a severe disease with high mortality resulting from excessive inflammation in the infected liver. Clinical interventions have been inefficient due to the lack of knowledge for inflammatory pathogenesis in the virus-infected liver. We show that wild-type mice infecte...

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Bibliographic Details
Main Authors: Guo, Sheng, Yang, Chengying, Diao, Bo, Huang, Xiaoyong, Jin, Meihua, Chen, Lili, Yan, Weiming, Ning, Qin, Zheng, Lixin, Wu, Yuzhang, Chen, Yongwen
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569300/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569300/

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