Human Genes Encoding Transcription Factors and Chromatin-Modifying Proteins Have Low Levels of Promoter Polymorphism: A Study of 1000 Genomes Project Data
The expression level of each gene is controlled by its regulatory regions, which determine the precise regulation in a tissue-specific manner, according to the developmental stage of the body and the necessity of a response to external stimuli. Nucleotide substitutions in regulatory gene regions may...
Main Authors: | Ignatieva, Elena V., Levitsky, Victor G., Kolchanov, Nikolay A. |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568383/ |
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