An Efficient Estimator of the Mutation Parameter and Analysis of Polymorphism from the 1000 Genomes Project

The mutation parameter θ is fundamental and ubiquitous in the analysis of population samples of DNA sequences. This paper presents a new highly efficient estimator of θ by utilizing the phylogenetic information among distinct alleles in a sample of DNA sequences. The new estimator, called Allelic BL...

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Bibliographic Details
Main Author: Fu, Yunxin
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198917/