Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide–gated channels

Replacement of a single proline with threonine gives rise to an altered conformation of the Drosophila CNG channel selectivity filter that leads to weak Ca2+ block of monovalent ion current.

Bibliographic Details
Main Authors: Lam, Yee Ling, Zeng, Weizhong, Derebe, Mehabaw Getahun, Jiang, Youxing
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555469/