Identifying novel sequence variants of RNA 3D motifs

Predicting RNA 3D structure from sequence is a major challenge in biophysics. An important sub-goal is accurately identifying recurrent 3D motifs from RNA internal and hairpin loop sequences extracted from secondary structure (2D) diagrams. We have developed and validated new probabilistic models fo...

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Bibliographic Details
Main Authors: Zirbel, Craig L., Roll, James, Sweeney, Blake A., Petrov, Anton I., Pirrung, Meg, Leontis, Neocles B.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551918/