Kaempferol Suppresses Transforming Growth Factor-β1–Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-1791
Kaempferol, a natural dietary flavonoid, is well known to possess chemopreventive and therapeutic anticancer efficacy; however, its antimetastatic effects have not been mechanistically studied so far in any cancer model. This study was aimed to investigate the inhibitory effect and accompanying mech...
Main Authors: | Jo, Eunji, Park, Seong Ji, Choi, Yu Sun, Jeon, Woo-Kwang, Kim, Byung-Chul |
---|---|
Format: | Online |
Language: | English |
Published: |
Neoplasia Press
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547409/ |
Similar Items
-
The British veterinary profession, 1791—1948
by: Lane, Joan
Published: (1985) -
The botanic garden, Erasmus Darwin, 1791
Published: (1977) -
Seven minor notes. 1788—1791
by: Kant I.
Published: (2012-10-01) -
Smad3 Sensitizes Hepatocelluar Carcinoma Cells to Cisplatin by Repressing Phosphorylation of AKT
by: Zhou, Hong-Hao, et al.
Published: (2016) -
AKT phosphorylates H3-threonine 45 to facilitate termination of gene transcription in response to DNA damage
by: Lee, Jong-Hyuk, et al.
Published: (2015)