Kaempferol Suppresses Transforming Growth Factor-β1–Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-1791
Kaempferol, a natural dietary flavonoid, is well known to possess chemopreventive and therapeutic anticancer efficacy; however, its antimetastatic effects have not been mechanistically studied so far in any cancer model. This study was aimed to investigate the inhibitory effect and accompanying mech...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Neoplasia Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547409/ |