Kaempferol Suppresses Transforming Growth Factor-β1–Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-1791

Kaempferol, a natural dietary flavonoid, is well known to possess chemopreventive and therapeutic anticancer efficacy; however, its antimetastatic effects have not been mechanistically studied so far in any cancer model. This study was aimed to investigate the inhibitory effect and accompanying mech...

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Bibliographic Details
Main Authors: Jo, Eunji, Park, Seong Ji, Choi, Yu Sun, Jeon, Woo-Kwang, Kim, Byung-Chul
Format: Online
Language:English
Published: Neoplasia Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547409/