Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and treatment

Macrophages are a major cellular constituent of the tumour stroma and contribute to breast cancer prognosis. The precise role and treatment strategies to target macrophages remain elusive. As macrophage infiltration is associated with poor prognosis and high grade tumours we used the THP-1 cell line...

Full description

Bibliographic Details
Main Authors: Ward, Rebecca, Sims, Andrew H., Lee, Alexander, Lo, Christina, Wynne, Luke, Yusuf, Humza, Gregson, Hannah, Lisanti, Michael P., Sotgia, Federica, Landberg, Göran, Lamb, Rebecca
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546497/