High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant

by Farnie, Gillian, Sotgia, Federica, Lisanti, Michael P.
Published 2015

Mitochondrial oxidative stress drives tumor progression and metastasis: should we use antioxidants as a key component of cancer treatment and prevention?

by Sotgia, Federica, Martinez-Outschoorn, Ubaldo E, Lisanti, Michael P
Published 2011

Cancer Metabolism: New Validated Targets for Drug Discovery

by Sotgia, Federica, Martinez-Outschoorn, Ubaldo E., Lisanti, Michael P.
Published 2013

Genetic Induction of the Warburg Effect Inhibits Tumor Growth

by Sotgia, Federica, Martinez-Outschoorn, Ubaldo E., Lisanti, Michael P.
Published 2012

Carbonic anhydrase 9 (CA9) and redox signaling in cancer-associated fibroblasts: Therapeutic implications

by Chadwick, Amy L, Howell, Anthony, Sotgia, Federica, Lisanti, Michael P
Published 2013

Doxycycline and therapeutic targeting of the DNA damage response in cancer cells: old drug, new purpose

by Peiris-Pagès, Maria, Sotgia, Federica, Lisanti, Michael P.
Published 2015

Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells

by Peiris-Pagès, Maria, Sotgia, Federica, Lisanti, Michael P.
Published 2015

The reverse warburg effect in osteosarcoma

by Sotgia, Federica, Martinez-Outschoorn, Ubaldo E., Lisanti, Michael P.
Published 2014

Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment

by Sotgia, Federica, Martinez-Outschoorn, Ubaldo E, Pavlides, Stephanos, Howell, Anthony, Pestell, Richard G, Lisanti, Michael P
Published 2011

Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts

by Peiris-Pagès, Maria, Smith, Duncan L., Győrffy, Balázs, Sotgia, Federica, Lisanti, Michael P.
Published 2015

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition

by Lamb, Rebecca, Harrison, Hannah, Hulit, James, Smith, Duncan L., Lisanti, Michael P., Sotgia, Federica
Published 2014

Cancer stem cell metabolism

by Peiris-Pagès, Maria, Martinez-Outschoorn, Ubaldo E., Pestell, Richard G., Sotgia, Federica, Lisanti, Michael P.
Published 2016

Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide

by Quann, Kevin, Gonzales, Donna M., Mercier, Isabelle, Wang, Chenguang, Sotgia, Federica, Pestell, Richard G., Lisanti, Michael P., Jasmin, Jean-François
Published 2013

Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)

by Fiorillo, Marco, Lamb, Rebecca, Tanowitz, Herbert B., Cappello, Anna Rita, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Published 2016

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth

by Capparelli, Claudia, Whitaker-Menezes, Diana, Guido, Carmela, Balliet, Renee, Pestell, Timothy G., Howell, Anthony, Sneddon, Sharon, Pestell, Richard G., Martinez-Outschoorn, Ubaldo, Lisanti, Michael P., Sotgia, Federica
Published 2012

CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angioge...

by Capparelli, Claudia, Chiavarina, Barbara, Whitaker-Menezes, Diana, Pestell, Timothy G., Pestell, Richard G., Hulit, James, Andò, Sebastiano, Howell, Anthony, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Published 2012

Metabolic remodeling of the tumor microenvironment: Migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth

by Carito, Valentina, Bonuccelli, Gloria, Martinez-Outschoorn, Ubaldo E., Whitaker-Menezes, Diana, Caroleo, Maria Cristina, Cione, Erika, Howell, Anthony, Pestell, Richard G., Lisanti, Michael P., Sotgia, Federica
Published 2012

Graphene oxide selectively targets cancer stem cells, across multiple tumor types: Implications for non-toxic cancer treatment, via “differentiation-based nano-therapy”

by Fiorillo, Marco, Verre, Andrea F., Iliut, Maria, Peiris-Pagés, Maria, Ozsvari, Bela, Gandara, Ricardo, Cappello, Anna Rita, Sotgia, Federica, Vijayaraghavan, Aravind, Lisanti, Michael P.
Published 2015

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease

by Lamb, Rebecca, Ozsvari, Bela, Lisanti, Camilla L., Tanowitz, Herbert B., Howell, Anthony, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Published 2015

Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction

by Lamb, Rebecca, Harrison, Hannah, Smith, Duncan L., Townsend, Paul A., Jackson, Thomas, Ozsvari, Bela, Martinez-Outschoorn, Ubaldo E., Pestell, Richard G., Howell, Anthony, Lisanti, Michael P., Sotgia, Federica
Published 2015