Endosialin Expression in Metastatic Melanoma Tumor Microenvironment Vasculature: Potential Therapeutic Implications

Ontuxizumab (MORAb-004) is a humanized recombinant antibody targeting endosialin (TEM-1, CD248). We conducted an analysis of endosialin expression in metastatic melanoma specimens using the anti-endosialin rat anti- MAb 9G5, in order to determine the potential of endosialin as a therapeutic target w...

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Bibliographic Details
Main Authors: Kiyohara, Eiji, Donovan, Nicholas, Takeshima, Ling, Huang, Sharon, Wilmott, James S., Scolyer, Richard A., Jones, Peter, Somers, Elizabeth B., O’Shannessy, Daniel J., Hoon, Dave S. B.
Format: Online
Language:English
Published: Springer Netherlands 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542822/