Endosialin Expression in Metastatic Melanoma Tumor Microenvironment Vasculature: Potential Therapeutic Implications
Ontuxizumab (MORAb-004) is a humanized recombinant antibody targeting endosialin (TEM-1, CD248). We conducted an analysis of endosialin expression in metastatic melanoma specimens using the anti-endosialin rat anti- MAb 9G5, in order to determine the potential of endosialin as a therapeutic target w...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Springer Netherlands
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542822/ |