Influence of tumor microenvironment on prognosis in colorectal cancer: Tissue architecture-dependent signature of endosialin (TEM-1) and associated proteins

Tumor survival is influenced by interactions between tumor cells and the stromal microenvironment. One example is Endosialin (Tumor Endothelial Marker-1 (TEM-1) or CD248), which is expressed primarily by cells of mesenchymal origin and some tumor cells. The expression, as a function of architectural...

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Bibliographic Details
Main Authors: O'Shannessy, Daniel J., Somers, Elizabeth B., Chandrasekaran, Lakshmi K., Nicolaides, Nicholas C., Bordeaux, Jennifer, Gustavson, Mark D.
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147300/