Redefining the transcriptional regulatory dynamics of classically and alternatively activated macrophages by deepCAGE transcriptomics

Classically or alternatively activated macrophages (M1 and M2, respectively) play distinct and important roles for microbiocidal activity, regulation of inflammation and tissue homeostasis. Despite this, their transcriptional regulatory dynamics are poorly understood. Using promoter-level expression...

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Bibliographic Details
Main Authors: Roy, Sugata, Schmeier, Sebastian, Arner, Erik, Alam, Tanvir, Parihar, Suraj P., Ozturk, Mumin, Tamgue, Ousman, Kawaji, Hideya, de Hoon, Michiel J. L., Itoh, Masayoshi, Lassmann, Timo, Carninci, Piero, Hayashizaki, Yoshihide, Forrest, Alistair R. R., Bajic, Vladimir B., Guler, Reto, Consortium, FANTOM, Brombacher, Frank, Suzuki, Harukazu
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538831/