CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes

Standard culture of human induced pluripotent stem cells (hiPSCs) requires basic Fibroblast Growth Factor (bFGF) to maintain the pluripotent state, whereas hiPSC more closely resemble epiblast stem cells than true naïve state ES which requires LIF to maintain pluripotency. Here we show that chemokin...

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Bibliographic Details
Main Authors: Hasegawa, Yuki, Tang, Dave, Takahashi, Naoko, Hayashizaki, Yoshihide, Forrest, Alistair R. R., the FANTOM consortium, Suzuki, Harukazu
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067614/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067614/

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