Getting the genome in shape: the formation of loops, domains and compartments

The hierarchical levels of genome architecture exert transcriptional control by tuning the accessibility and proximity of genes and regulatory elements. Here, we review current insights into the trans-acting factors that enable the genome to flexibly adopt different functionally relevant conformatio...

Full description

Bibliographic Details
Main Authors: Bouwman, Britta AM, de Laat, Wouter
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536798/