Ca2+ Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca2+-Dependent Nuclear Gene Expression
In polarized cells or cells with complex geometry, clustering of plasma-membrane (PM) ion channels is an effective mechanism for eliciting spatially restricted signals. However, channel clustering is also seen in cells with relatively simple topology, suggesting it fulfills a more fundamental role i...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Cell Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521080/ |