In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry

The possibility of directly converting non-neuronal cells into neurons in situ in the brain would open therapeutic avenues aimed at repairing the brain after injury or degenerative disease. We have developed an adeno-associated virus (AAV)-based reporter system that allows selective GFP labeling of...

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Bibliographic Details
Main Authors: Torper, Olof, Ottosson, Daniella Rylander, Pereira, Maria, Lau, Shong, Cardoso, Tiago, Grealish, Shane, Parmar, Malin
Format: Online
Language:English
Published: Cell Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521079/