Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide*

Background: CD8+ T-cells play a central role in type 1 diabetes (T1D) by recognizing insulin peptides displayed by MHC.

Bibliographic Details
Main Authors: Motozono, Chihiro, Pearson, James A., De Leenheer, Evy, Rizkallah, Pierre J., Beck, Konrad, Trimby, Andrew, Sewell, Andrew K., Wong, F. Susan, Cole, David K.
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521012/