Partially Evoked Epithelial-Mesenchymal Transition (EMT) Is Associated with Increased TGFβ Signaling within Lesional Scleroderma Skin
The origin of myofibroblasts in fibrotic conditions remains unknown and in systemic sclerosis (SSc) it has been proposed that activation of local fibroblasts, trans-differentiation of perivascular or vascular cells, recruitment of fibrocyte progenitors, or epithelial to mesenchymal transition (EMT)...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517793/ |