Paclitaxel Modulates TGFβ Signaling in Scleroderma Skin Grafts in Immunodeficient Mice

In a mouse model of Systemic sclerosis low-dose paclitaxel can suppress an important disease-related pathway, that involves TGFβ and Smad, and lessen fibrosis .

Bibliographic Details
Main Authors: Liu, Xialin, Zhu, Shoukang, Wang, Tao, Hummers, Laura, Wigley, Fredrick M, Goldschmidt-Clermont, Pascal J, Dong, Chunming
Format: Online
Language:English
Published: Public Library of Science 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274282/