Paclitaxel Modulates TGFβ Signaling in Scleroderma Skin Grafts in Immunodeficient Mice
In a mouse model of Systemic sclerosis low-dose paclitaxel can suppress an important disease-related pathway, that involves TGFβ and Smad, and lessen fibrosis .
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274282/ |