Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples

Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples

Current genomic studies are limited by the availability of fresh tissue samples. Here, we show that Illumina RNA sequencing of formalin-fixed diagnostic tumor samples produces gene expression that is strongly correlated with matched frozen tumor samples (r > 0.89). In addition, sequence variation...

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Bibliographic Details
Main Authors: Graw, Stefan, Meier, Richard, Minn, Kay, Bloomer, Clark, Godwin, Andrew K., Fridley, Brooke, Vlad, Anda, Beyerlein, Peter, Chien, Jeremy
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511951/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511951/

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