A Tutorial on Target-Mediated Drug Disposition (TMDD) Models
Target-mediated drug disposition (TMDD) is the phenomenon in which a drug binds with high affinity to its pharmacological target site (such as a receptor) to such an extent that this affects its pharmacokinetic characteristics.1 The aim of this Tutorial is to provide an introductory guide to the mat...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
John Wiley & Sons, Ltd
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505827/ |