Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorocuracil in HT-29 Colon Cancer Cells

Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorocuracil in HT-29 Colon Cancer Cells

5-Fluorouracil (5-FU) is commonly used for the therapy of colon cancer; however, acquired resistance to 5-FU is a critical barrier to successful treatment and the primary cause of chemotherapy failure. Epithelialmesenchymal transition (EMT) is a process whereby cells undergo alterations in morpholog...

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Bibliographic Details
Main Authors: Kim, A-Young, Kwak, Jae-Hwan, Je, Nam Kyung, Lee, Yun-hee, Jung, Young-Suk
Format: Online
Language:English
Published: The Korean Society Of Toxicology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505345/

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